产品货号：
Z33401
中文名称：
ATP2C1抗体
英文名称：
Anti-ATP2C1 Antibody (Clone#4G12)
产品规格：
100μl
发货周期：
1～3天
产品价格：
询价
| 抗体名称 | Anti-ATP2C1 Antibody (Clone#4G12) |
| 指标别名 | ATP dependent Ca(2+) pump PMR1;ATP2C1;ATP2C1A;ATPase 2C1;HHD;hSPCA1;KIAA1347;PMR1;PMR1L;SPCA1 |
| 克隆性 | Monoclonal |
| 检验物种 | human,monkey |
| 应用范围 | WB,IHC,ELISA |
| 基因名称 | ATP2C1 |
| 克隆号 | 4G12 |
| 抗体来源 | Mouse |
| 抗体类型 | IgG |
| 免疫原 | Purified recombinant fragment of PMR1 expressed in E.Coli. |
| 计算分子量 | 101KD |
| 成分 | Ascitic fluid containing 0.03% sodium azide. |
| 纯化方式 | Affinity purification |
| 浓度 | 1mg/mL |
| 产品形态 | 溶液 |
| 保存条件 | -20℃可保存1年，短期保存或频繁使用请置于4℃，可保存一个月，避免反复冻融。 |
| 背景资料 | ATP2C1,also known as secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1,belongs to the family of P-type cation transport ATPases.This magnesium-dependent enzyme catalyzes the hydrolysis of ATP coupled with the transport of the calcium from the cytosol to the Golgi lumen.Defects in this gene cause Hailey-Hailey disease,an autosomal dominant disorder characterized by persistent blisters and erosions of the skin.Unlike the related protein ATP2C2,ATP2C1 is ubiquitously expressed and displays a lower maximal turnover rate for overall Ca2+-ATPase reaction and a higher apparent affinity for cytosolic Ca2+ activation of phosphorylation.Recent evidence suggests that ATP2C1 is a key regulator of insulin-like growth factor receptor (IGF1R) processing in tumor progression in basal breast cancers. |
| Uniprot ID | P98194 |
| 基因名全称 | Calcium-transporting ATPase type 2C member 1 |
| 蛋白名全称 | Calcium-transporting ATPase type 2C member 1 |
| 推荐稀释比 | WB 1:500～1:2000 IHC 1:200～1:1000 ELISA 1:10000 |
相关搜索：ATP2C1抗体，ATP2C1单抗，Anti-ATP2C1 Antibody (Clone#4G12)